Starting Treatment at Discharge for Alcohol-Related Hospital Stays Shows Benefits However, only 2% of hospitalized patients received a script Mar 29, 2024
VCTE-Based Agile Scores Accurate in Predicting Liver-Related Events in MASLD Serial Agile scores were also accurate over time Mar 25, 2024
Aspirin Cuts Liver Fat in Preliminary MASLD Trial At 6 months, 42.5% of patients on low-dose aspirin had at least a 30% reduction in hepatic fat Mar 20, 2024
FDA Approves First-Ever Drug for Serious Liver Condition Resmetirom indicated for NASH patients with liver scarring Mar 14, 2024
Deaths Due to Alcohol Use; Steps for the Sedentary Also in TTHealthWatch: microplastics in arteries, and worldwide obesity and diabetes risk Mar 09, 2024 podcast
Semaglutide Cuts Liver Disease Severity in People With HIV Weekly injections reduced liver fat by 31% at 6 months Mar 08, 2024
SGLT2 Inhibitors Tied to Better NAFLD Outcomes vs Other Antidiabetic Agents Class of drug associated with highest odds of NAFLD regression for patients with type 2 diabetes Feb 14, 2024
New Treatment for NASH; Human Milk for Preterm Infants Also in TTHealthWatch: managing gout with uric acid levels Feb 10, 2024 podcast
Stigmatizing Language Common on Liver Transplant Websites Researchers searched for terms including "alcoholic," "alcoholism," and "alcohol abuse" Feb 08, 2024
Resmetirom Poised to Become First NASH Treatment Phase III study demonstrated drug is effective in resolving NASH and improving liver fibrosis Feb 07, 2024
Undiagnosed Liver Disease May Be Common in Patients With Dementia Hepatic encephalopathy could be contributing to cognitive symptoms, study suggested Jan 31, 2024
Can the Eye Reveal Cardiac and Lung Disease -- Plus Much More? Researchers link thinner retinal layers to higher risk of multiple diseases Jan 26, 2024
HAIP Chemo Offers OS Advantage in Advanced Intrahepatic Cholangiocarcinoma One in three trial patients still alive at 3 years after hepatic arterial infusion pump treatment Jan 20, 2024
First-Ever Experiment Shows How Pigs Could One Day Help Liver Failure Patients Penn surgeons externally attached gene-edited pig liver to brain-dead human Jan 19, 2024
Subclasses of Steatotic Liver Disease Can Help Determine Prognosis Risk of liver decompensation increased progressively when alcohol intake came into play Jan 18, 2024
Lenvatinib-Pembrolizumab Combo Misses Goal in First-Line HCC Trial Numerical advantages in OS, PFS fall short of statistical significance Dec 13, 2023
Mahvash Disease Case Resolved With Liver Transplantation Rare disease should be part of the differential in the presence of massive pancreaticomegaly Nov 22, 2023
PPAR Agonist Led to 'Clinically Meaningful' Improvement in PBC-Related Pruritus Seladelpar also improved markers of disease activity versus placebo Nov 15, 2023
Novel MASH Drug Reduces Liver Fat in Mid-Stage Trial At highest dose, thyroid hormone receptor-beta agonist decreased liver fat content by 45% Nov 15, 2023
Emergency Liver Transplant Effective for Severe Acute-on-Chronic Liver Failure 1-year survival reached 78% for patients who received an emergency transplant Nov 14, 2023
Novel Drug Makes Its Case for Pretreated Primary Biliary Cholangitis In randomized trial, oral elafibranor induced biochemical response at 1 year in 51% of patients Nov 14, 2023
AKI Response Tied to Improved Survival for Patients Waiting on Liver Transplant Results highlight the importance of prompt recognition and treatment of acute kidney injury Nov 13, 2023
MASLD Predicted to Increase by 23% by Middle of the Century AASLD president: "No way we are going to be able to transplant our way out of this" Nov 12, 2023
Diet and Liver Health; Gut Microbiome and Cardiometabolic Disease Also in TTHealthWatch: COVID hospitalization data Oct 14, 2023 podcast
Cancer Risk in NAFLD Higher With Early Disease Onset 52% greater risk of malignancy for patients diagnosed with fatty liver disease before age 45 Sep 27, 2023
Gene Therapy Promising for Rare Jaundice Syndrome Early-phase data suggest a dose that can keep bilirubin in check without hours of phototherapy Aug 16, 2023
FDA OKs First Liver-Directed Treatment for Metastatic Uveal Melanoma Hepzato Kit melphalan delivery system produced objective responses in 36% of patients Aug 15, 2023
Aspartame Is a 'Possible' Carcinogen, WHO Declares But the organization's recommended limits on aspartame consumption remain unchanged Jul 13, 2023
NAFLD and T2DM Bodes Higher Risk of Liver Decompensation, Cancer Several-fold higher risks compared with NAFLD patients without diabetes Jul 11, 2023
'Jarringly' Low Hep C Cure Rates a Decade After New Treatments, CDC Says Lack of rapid testing and payer restrictions are creating barriers, experts say Jun 29, 2023
Novel Triple Agonist Nabs Biggest Weight Loss Yet in Obesity Trial Plus, two other studies on retatrutide show benefit in type 2 diabetes, fatty liver disease Jun 26, 2023
Can AI Help Determine if Liver Cancer Will Respond to Standard Treatment? Early model suggests a way to predict progression-free survival Jun 26, 2023
Fecal Matter Transplant Shows Promise in Cirrhosis Pilot trial demonstrates that FMT can boost gut health, prevent serious infections Jun 25, 2023
'Game Changer' in NASH: Resmetirom Hits Endpoints in Pivotal Study Investigational drug more likely to resolve severe form of fatty liver disease, improve fibrosis Jun 22, 2023
Ocaliva for NASH Gets Thumbs Down From FDA Advisors Difficulty of risk mitigation for potential drug-induced liver injury weighed heavily on members May 19, 2023
NASH Drug Candidate Comes With 'Serious Risks,' Says FDA Staff Agency reviewers signal little support for first potential nonalcoholic steatohepatitis drug May 17, 2023
Statins Linked to Slower Liver Disease Progression Risk 40% lower with use among those with preexisting liver disease, study found May 04, 2023
Bariatric-Metabolic Surgery More Effective Than Lifestyle Change for NASH Roux-en-Y bypass or sleeve gastrectomy resolved NASH without exacerbating liver fibrosis Apr 26, 2023
Transplant Chief Was an Organ Recipient Herself Years ago, she had a liver transplant. Now she leads Hopkins' pediatric liver transplant program Apr 19, 2023
NKF Roundup: Latest Data on Tolvaptan, Terlipressin, and Lumasiran More research from the National Kidney Foundation Spring Clinical Meeting Apr 17, 2023