New Clue to Anti-PD-L1 Activity in Breast Cancer? Survival benefit with durvalumab in patients with PDL1 copy number alteration May 26, 2020
Biologics Don't Increase Melanoma Risk... Probably Meta-analysis offers some reassurance, but leaves room for doubt May 20, 2020
Avelumab Flops Again in Ovarian Cancer Another negative phase III trial, now in the first-line setting May 19, 2020
PARP Inhibitors Still Work in HRD-Low Ovarian Cancer In VELIA, homologous recombination deficiency score prognostic but not predictive May 14, 2020
KRAS May Predict Benefit of MEK Inhibitors in Some Ovarian Cancers Nearly 7-month PFS boost in patients with KRAS mutations May 11, 2020
Five Days of G-CSF Adequate for Breast Cancer Chemo Rate of chemotherapy-induced febrile neutropenia similar to 7- to 10-day regimen May 08, 2020
Face-Aging Selfies Help Modify Risky Skin Behaviors for Teens Trial looked at effects of a free "UV-selfie" app May 07, 2020
BMI, Weight Change Linked to Prostate Ca Outcomes Gain or loss of body weight both show risk May 07, 2020
Blood Test Promising as Colorectal Cancer Screen In early study, better numbers than with current alternatives to colonoscopy May 07, 2020
Ranitidine Cancer Risk: Health Records Offer Reassurance Huge study finds no indication that nitrosamine contamination affected real-world outcomes May 05, 2020
Honing Chemo Use in Small Breast Tumors Clearest survival benefit for 8-10 mm tumors in HR/HER2-positive disease May 03, 2020
Nivolumab-Based Tx Effective in Early, Unfavorable Hodgkin's Interim results showed high CR rates and almost 100% PFS, OS at 12 months May 01, 2020
6-Week Keytruda Safe, Effective in Melanoma Schedule gets FDA approval for all adult indications Apr 30, 2020
Talzenna Misses OS Endpoint in BRCA-Positive Breast Cancer But PARP inhibitor improved patient-reported outcomes over standard therapy Apr 29, 2020
COVID-19 Mortality Spikes in Patients With Lung, Blood Cancers Those with metastatic disease also at special risk for poor outcomes Apr 28, 2020
Anti-PD-L1 Plus PARP Inhibitor Ups Response in Breast Cancer Add-on treatment superior to chemo alone, but questions remain about cost, toxicity Apr 28, 2020
Triplet Succeeds in BRAF-Mutant Melanoma Immunotherapy plus BRAF/MEK inhibition boosts PFS over targeted agents alone Apr 27, 2020
Add-On Metformin No Help in Advanced Endometrial Cancer Trial highlights deep racial disparities in treatment response, survival outcomes Apr 27, 2020
Hormone Levels Tied to Future Breast Cancer Risk "New avenues for exploration" in risk stratification Apr 24, 2020
Herceptin Boosts OS in HER2-Positive Uterine Cancer New data bolster targeted approach for aggressive tumor type Apr 24, 2020
New Standard in Recurrent, Platinum-Sensitive Ovarian Cancer Pegylated liposomal doxorubicin unseats gemcitabine in standard platinum regimen Apr 21, 2020
Breastfeeding Tied to Lower Ovarian Cancer Risk Lower incidence of borderline tumors as well Apr 02, 2020
Blood Test Spot On for HPV Cancer Recurrence Near-100% accuracy for ruling in or out recurrent oropharyngeal cancer Apr 01, 2020
How Prevalent Is Checkpoint Inhibitor Thyroid Dysfunction, Really? Real-world data offer word of caution for oncologists Apr 01, 2020
Post-Op HPV Vaccine Cuts Cervical Precancer Recurrences Plus osteoporosis in gynecologic cancer survivors, and a novel approach to CIN2/3 Mar 31, 2020
DOAC Works in Cancer-Related VTE, No Tradeoff in Bleeds Apixaban monotherapy matches dalteparin in non-inferiority trial Mar 29, 2020
Study: Any Polyps Raise Risk of Colorectal Cancer Only three types, however, increased mortality Mar 23, 2020
CRC: Upfront, Re-Introduction of FOLFOXIRI Most Effective, but at What Cost? Modest survival improvement comes with side effects, toxicity even in healthiest patients Mar 13, 2020
Beyond CDK4/6 Inhibitors for HR-Positive Breast Cancer Switching drugs, taking aim at different targets under investigation Mar 11, 2020
No DNA Damage Seen With Single Low-Dose CT Scan Some reassurance for annual lung cancer screening safety Mar 10, 2020
Immunotherapy Super-Responder: What Is Life, Not Exactly Cured? Lisa Geller's cancer has been gone nearly 4 years, but life has been far from normal Mar 02, 2020
Bringing Transplant to More Patients With AML Conditioning with radiolabeled antibody leads to successful transplantation in 84% of older patients Feb 25, 2020
New CAR-T Makes Case for Aggressive Lymphomas Largest trial to date shows 73% ORR, 53% CR, potential for outpatient treatment Feb 25, 2020
Stem-Cell Transplant Trial Ends in a Draw Similar PFS with haploidentical bone marrow, double unrelated umbilical cord blood Feb 24, 2020
Docs Said It Was Cancer; She Didn't Believe Them, and She Was Right What a 60-year-old refugee taught me about skepticism of medical professionals Feb 24, 2020
Preemptive Anti-IL-6 May Cut Severe CRS With CAR-T Tx Targeting patients with high tumor burden reduced severe CRS by 50% Feb 22, 2020
Myeloablative Therapy Prevails in AML Transplant Study Better survival, fewer relapses compared with reduced-intensity conditioning Feb 21, 2020
Better Quality CR With One AML Therapy vs Another? Longer survival after CR/CRi with CPX-351 than with 7+3 in patients with AML-MRC Feb 21, 2020