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Latest Medical News

Children OK with Long-Term Exjade

ATLANTA -- Children with thalassemia and treated with the anti-iron overload drug deferasirox (Exjade) appear to tolerate the treatment for at least as long as 3 years while serum iron levels fell, researchers said here.

Statins May Slow Inflammatory Breast Cancer

SAN ANTONIO -- Inflammatory breast cancer grew significantly more slowly in women who had a history of treatment with statin drugs, findings from a large retrospective review showed.

Cardio Notes: Stress Test Finds Heart Disease in Seniors

Researchers are taking a second look at the accuracy of treadmill exercise testing for women over 65. Also this week, the birth of a subspecialty for adults with congenital heart disease and leg artery stenting.

Extended Apixaban Stops VTE Recurrence

ATLANTA -- Apixaban taken for an additional year after standard venous thromboembolism (VTE) treatment reduced recurrent events in a placebo-controlled trial, researchers said.

C. Difficile Inpatient Stays Long, Costly

LAS VEGAS -- Among the many factors that contribute to the burgeoning costs associated with Clostridium difficile infections are long hospital stays, particularly in intensive care units, and the need for multiple specialist consultations, a chart review determined.

Polycythemia Vera Better with Low Hematocrit

ATLANTA -- Maintaining patients with polycythemia vera at hematocrit levels below 45% reduced thrombotic complications without increasing rates of other serious adverse events.

FDA Panel Gives Thumbs Down to Opioid

SILVER SPRING, Md. -- An FDA advisory committee voted 11-2 on Friday against recommending approval of a single-entity hydrocodone product, raising questions about its abuse potential.

Melanoma Tx Ups Survival, but Very Pricey

LAS VEGAS -- The oral BRAF inhibitor vemurafenib (Zelboraf) increased survival in patients with metastatic melanoma, but the cost may not justify its use in a state Medicaid program, an analysis suggested.

ALS Drug Gets Review for VA Coverage

LAS VEGAS -- Riluzole (Rilutek) should remain on the Veterans Administration formulary as a treatment for patients with amyotrophic lateral sclerosis, despite having only modest benefits and considerable cost, a researcher said here.

Enbrel Best Buy Among Anti-TNFs

LAS VEGAS -- The tumor necrosis factor inhibitor etanercept (Enbrel) was more cost-effective for the treatment of rheumatoid arthritis than were two other biologic agents in this class, a budget impact analysis found.

FDA to Look at Tainted Skin Preps

Antiseptic skin preparation products can be contaminated by microbes, a problem the FDA will address at an upcoming public hearing.

High-Dose Zofran Pulled From Market

WASHINGTON -- The 32-mg dose of the anti-nausea drug ondansetron (Zofran) has been pulled from the market because of concerns about cardiac problems, the FDA announced Tuesday.

Injector Pen May Ease Emergency Seizure Tx

SAN DIEGO -- An investigational pen-type injector for delivering intramuscular diazepam appeared safe and effective for home treatment of acute seizures, researchers said here.

Type of Contrast May Mean More Comfortable CT

CHICAGO -- Patients who underwent abdominal or pelvic CT imaging with a low-osmolar contrast agent reported more discomfort during the exam than patients who received an iso-osmolar agent, researchers said here.

Repeat CT Scans May Up Breast Ca Risk in Young Women

CHICAGO -- A female teenager who undergoes multiple chest or cardiac CT studies may see her 10-year risk for breast cancer double, researchers said here.

Climbers Face Lasting Effects if Brain Swells

CHICAGO -- Extreme mountaineers who develop serious brain swelling at altitude appear to have lasting evidence of small hemorrhages in their brains, researchers said here.

'Scatter' Effects of Mammography Pose Little Risk

CHICAGO -- Scatter radiation from screening mammography is minimal, even to the thyroid, and results in negligible risk to the patient, researchers reported here.

Why the iPad Mini is the Perfect Prescription for Doctors

Lupus Patients Tend to Skip Pap Tests

WASHINGTON -- Women with systemic lupus erythematosus do not appear undergo timely cervical cancer screening despite being at an increased risk for cervical dysplasia and HPV infection, researchers said here.

Advair: How Safe Is This Drug?

The asthma drug Advair is used by millions of patients worldwide and for many patients it is an effective treatment, but the drug is often used as first line therapy, an unapproved and possibly dangerous indication as this investigation by MedPageToday/Milwaukee Journal Sentinel reveals.

TB No Barrier to Anti-TNF Treatment

WASHINGTON -- Patients being treated with tumor necrosis factor inhibitors who develop tuberculosis may safely reinstitute their biologic before completing the lengthy TB treatment regimen, a retrospective study suggested.

Compounder Tied to Tainted Eye Meds, Lost Sight

CHICAGO -- All but one of 12 patients given injections of contaminated bevacizumab (Avastin) prepared by a compounding pharmacy permanently lost vision in the affected eye, researchers reported here.

Enbrel Best for RA If Taken Over Long Term

WASHINGTON -- Most rheumatoid arthritis patients who achieve a state of low disease activity taking etanercept (Enbrel) fare better if they remain on therapy, even if only at a lower dose, a researcher reported here.

Food Allergies Cost Society a Bundle

ANAHEIM, Calif. -- The economic cost of food allergy in an average American child tops $4,000, with less than 20% of that attributable to direct medical expenses, a researcher said here.

Eating Before Lipid Test OK

It may not be necessary to fast before a routine cholesterol check, a large community-based population study suggested.

Combo Drug for Nasal Allergy Tops Single Tx

ANAHEIM, Calif. -- A nasal spray combining a corticosteroid and an antihistamine was better than either drug alone for relieving allergic rhinitis in a comparison with "real-world鈥� commercial products, a researcher said here.

Early Stroke Risk After Hip Replacement

Patients undergoing a total hip replacement appear to have an elevated risk of stroke in the weeks following the operation, researchers found.

FDA Panel Wary on Making Bladder Control Drug OTC

WASHINGTON -- An FDA advisory panel on Friday voted against recommending making oxybutynin transdermal patch (Oxytrol) available over-the-counter for overactive bladder in women.

Meningitis: FDA Warns of 'Light Therapy' Claims

A Tennessee company made false claims that its "light therapy" has benefits for fungal meningitis, the FDA said.

AHA: No Excess Bleeding Risk with Dabigatran

LOS ANGELES -- Patients starting dabigatran (Pradaxa) did not have a higher risk of bleeding compared with new users of warfarin, according to a postmarketing data review by the FDA.

Fainting in PE Signals High Risk

ATLANTA -- Patients with pulmonary embolism brought to emergency rooms because they had passed out tended to have the most ominous risk factors for poor outcomes, a researcher said here.

Mother Marianne Cope Canonized for Work with Leprosy

Colon Cancer Risk Rises After Endometrial Ca

LAS VEGAS -- A history of endometrial cancer at a younger age quadrupled the likelihood of a subsequent diagnosis of colorectal cancer, a retrospective analysis of administrative data showed.

Drug Relieves Opioid-Induced Constipation

LAS VEGAS -- An investigational opioid antagonist provided effective and durable relief from opioid-induced constipation in patients with chronic pain without interfering with analgesia, a randomized trial showed.

Novel Drug Stars in Phase III PAH Trial

ATLANTA -- Macitentan, a next-generation endothelin receptor antagonist for pulmonary arterial hypertension, met its efficacy endpoint and was said to be well tolerated in a large clinical trial.

Child Booster Seat Laws Work

锘縉EW ORLEANS -- States that implemented booster seat laws saw a drop in serious injuries from motor vehicle crashes among children ages 4 to 8 during a recent 11-year period, researchers found.锘�

BP Drug Linked to Severe Diarrheal Illness

LAS VEGAS -- A patient's insightful question led to the identification of almost two dozen cases of severe enteropathy associated with use of blood pressure medication, investigators reported here.

Subjective Effects Drive COPD Outcomes

ATLANTA -- For patients with COPD, their own assessment of breathing problems is more predictive of outcomes than spirometry or doctor-diagnosed exacerbations, a researcher said here.

Cardio Notes: Sex Improves with Stenting

Opening the arteries of those with stable coronary disease also opens the door to an improved sex life. Also this week, bariatric surgery helps remodel the heart.

Recall: Device Sucks Life From Patient

A suction system for collecting surgical waste apparently killed one patient and seriously injured another, prompting its maker to recall it and several related devices, the FDA said.

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