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General Neurology

News, opinions and meeting coverage in neurology.

FDA APPROVED eladocagene exuparvovec-tneq (Kebilidi) over a computer rendering of nerve cells.

First Brain-Delivered Gene Therapy Approved for AADC Deficiency

Novel treatment is indicated for children and adults with the rare disorder

$An x-ray image of an intertrochanteric fracture of the left femur.$

Gabapentinoids Tied to Hip Fractures in Older Adults

Risk of hip fracture was high in people with frailty or chronic kidney disease

A photo of a seated mature woman holding onto a cane and a man鈥檚 hand.

Frailty Tied to Future Dementia

Trajectories accelerated 4 to 9 years before dementia onset

Neuro Break over a computer rendering of neurons.

Galantamine and Alzheimer's; Fork Sign Landmark; Instagram in Neurology Education

News and commentary from the world of neurology and neuroscience

AMA over a photo of Walt Disney World Swan and Dolphin Resort in Orlando, FL.

AMA Delegates Want Better Protection From Ionizing Radiation Exposure

Delegates express concerns that PPE doesn't always cover women, who are more at risk of exposure

A computer rendering of an antibody over amyloid plaques forming between neurons.

Alzheimer's Data Withdrawn

Researchers do not stand by claims made about lecanemab deaths

A photo of a female pediatric nurse interacting with a baby in an incubator.

Industry Clinic 鈥� Ad Insights

Shifting the Paradigm in Whole-Genome Sequencing for Newborns

A computer rendering of amyloid plaques forming between neurons.

Midlife Choices May Offset Genetic Risk for Dementia, Stroke, Late-Life Depression

Risk of common age-related brain diseases was reduced over 12-year follow-up

2024 YEAR IN REVIEW multiple sclerosis over a computer rendering of the demyelination of a neuron.

Year in Review: Multiple Sclerosis

A look back at newsworthy stories of 2024

A photo of a female nurse holding the hand of a senior male patient.

100 Days Trapped in Inpatient Legal Limbo

Awaiting guardianship in the hospital long-term should not be the norm

Neuro Break over a computer rendering of neurons.

Weekend Warriors and Dementia; Iron Chelation and Alzheimer's; Neuro Drug Costs Rise

News and commentary from the world of neurology and neuroscience

CTAD

Alzheimer's Progression May Be Slowed by Targeted Magnetic Pulses, Study Suggests

In phase II trial, transcranial stimulation led to significant differences versus placebo

CTAD over a photo of Madrid Marriott Auditorium Hotel and Conference Center in Madrid, Spain.

Omega-3 Supplements Show Benefit in APOE4 Carriers

Trial finds DHA can penetrate the brain before dementia onset

2024 YEAR IN REVIEW tardive dyskinesia over a computer rendering of a dendrite receiving emitted neurotransmitters.

Year in Review: Tardive Dyskinesia

New VMAT2 formulations, case reports, screening tools, and long-term data in 2024

CTAD over a photo of Madrid Marriott Auditorium Hotel and Conference Center in Madrid, Spain.

Leukemia Drug Shows Promise in Dementia With Lewy Bodies

Cognitive outcomes, biomarkers improved with nilotinib in phase II trial

A photo of a high school football game.

We Can Better Protect Kids From Head Injury in Football

Making youth football safer requires a collective effort

Neuro Break over a computer rendering of neurons.

Alzheimer's Trials Investigated; Chronic Pain Predicted; Dementia Drugs and AMD

News and commentary from the world of neurology and neuroscience

A Moral Code: Ethical Dilemmas in Medicine

Three physicians face crossroads in patient care

Should I Offer My Patient the Option to End His Life?

The complexity of medical aid-in-dying laws

A computer rendering of a transparent human head with Broca鈥檚 area of the brain highlighted.

A Case of Broca's Aphasia

An excerpt from Theodore H. Schwartz's book, Gray Matters: A Biography of Brain Surgery

A computer rendering of amyloid plaques forming on nerve cells.

Ozempic Linked With Lower Risk of Alzheimer's Diagnosis

Large observational study suggests further research is warranted

EPA Imposes Stricter Standards to Protect Kids From Lead Paint Exposure

"There is no safe level of lead," said agency official

A computer rendering of single strands of RNA.

First Cases of New Neurology Syndrome Identified

Long non-coding RNA implicated in human disease

A computer rendering of amyloid plaques forming between nerve cells.

Poor Sleep at Age 40 Linked to Accelerated Brain Aging

Sleep quality in early midlife predicted brain age 15 years later

Neuro Break over a computer rendering of neurons.

MIND Diet and Cognitive Decline; Gene Therapy for Parkinson's; Curbing MS Fatigue

News and commentary from the world of neurology and neuroscience

A computer rendered cross section of the inner ear.

Hearing Loss May Signal Early Parkinson's Disease

Early interventions with hearing aids attenuated the risk

AANEM over a photo of Savannah Convention Center in Savannah, GA.

Daily Oral Edaravone for ALS No Better Than On/Off Regimen

Changes in CAFS, ALSFRS-R scores comparable at 48 weeks

AANEM over a photo of Savannah Convention Center in Savannah, GA.

Myasthenia Gravis Patients May Use Less Steroids After Starting Efgartigimod

Insurance claims data show lower glucocorticoid usage at 1 year

AANEM over a photo of Savannah Convention Center in Savannah, GA.

Sustained Disease Control in Adolescent Myasthenia Gravis With FcRn Blocker

Nipocalimab plus standard of care reduced IgG and was well tolerated

AANEM over a photo of Savannah Convention Center in Savannah, GA.

Gene Therapy Details Revealed in Duchenne Trial

Differences between delandistrogene moxeparvovec and placebo emerge in secondary outcomes

FDA APPROVED foscarbidopa and foslevodopa (Vyalev) over a computer rendering of Lewy bodies.

Continuous Parkinson's Disease Therapy Wins FDA Nod

Round-the-clock infusion delivers carbidopa and levodopa pro-drugs

Kids' Neurodevelopment Appears Unharmed by Maternal COVID Infection

Study may ease fears about potential neurodevelopmental effects of fetal COVID exposure

AANEM over a photo of Savannah Convention Center in Savannah, GA.

Nipocalimab Shows Sustained Efficacy in Myasthenia Gravis

Phase III trial met primary endpoint at 6 months

AANEM over a photo of Savannah Convention Center in Savannah, GA.

Anti-CD19 Monoclonal Antibody Shows Positive Results in Myasthenia Gravis

Topline phase III data show inebilizumab met primary endpoint

Neuro Break over a computer rendering of neurons.

Alzheimer's-Heparin Link; Two Phases of Alzheimer's Damage; Prion Disease Testing

News and commentary from the world of neurology and neuroscience

An image of a bottle of LEQUEMBI Injection single-dose vial

Alzheimer's Drug in Smaller Vial Sizes Could Save Medicare Hundreds of Millions

Nearly 6% of lecanemab may be discarded each year

A computer rendering of amyloid plaques forming on nerve cells.

Loneliness Tied to Alzheimer's and Dementia Risk

Feeling lonely also linked with cognitive impairment that's not dementia, meta-analysis shows

A computer rendering of stem cells and a strand of DNA.

Gene Therapy for Rare Brain Disease Effective, but Comes With Blood Cancer Risk

10% of patients in trials leading to eli-cel's approval developed MDS or AML

A computer rendering of nerve cells.

Some Cancers Occur More Frequently in Multiple Sclerosis Patients

Bladder, brain, and cervical cancer risks were higher in people with MS

A photo of a bag of red blood cells hanging from a rack.

Liberal Blood Transfusions Deliver Brain Function Benefit for the Critically Ill

Fewer cerebral ischemic events also observed with care teams quicker to give blood

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