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as monotherapy met its primary endpoint in a trial of major depressive disorder or bipolar depression with mixed features, significantly reducing symptoms and severity over 6 weeks versus placebo, said Intra-Cellular Therapies. The atypical antipsychotic is already approved for schizophrenia and bipolar-related depressive episodes.

in people 65 and older quadrupled from 2002 to 2021, jumping from 3 to 12 deaths per 100,000 population. More than half of the 6,702 deaths in 2021 involved an opioid. (JAMA Psychiatry)

People suffering from a lifetime of , according to a new study of blood markers presented at the European Congress of Psychiatry's annual meeting. "For example, people with bipolar disorder had blood markers indicating that they were around 2 years older than their chronological age," said lead study author Julian Mutz, PhD, of King's College London.

The FDA has approved the first over-the-counter naloxone (Narcan) product for reversing opioid overdoses, though some advocates are and stigma could be barriers. (New York Times).

In the 3 months following the Supreme Court's decision overturning Roe v. Wade, the prevalence of . "Mental health outcomes associated with restricting abortion access may extend broadly, beyond female individuals who have been denied an abortion to female individuals of reproductive age," researchers said in JAMA Network Open.

The FDA cleared GrayMatters Health's device -- for patients with post-traumatic stress disorder as an add-on to standard of care, the maker announced.

Among adolescents girls with depression and anxiety who were not on antidepressants, was linked with a reduced risk for self-harm, a population-based cohort study found. (Journal of Child Psychology and Psychiatry)

Some are now developing gambling addictions. (The Guardian)

Over a half century after the development of fluoxetine (Prozac), a may be more effective and quicker than their predecessor. (STAT)

Hundreds of will remain out of commission past the April 1 reopening deadline set by Gov. Kathy Hochul (D). (Politico)

prior to the age of 13 may have a genetic root cause, a study in Schizophrenia Research suggested.

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