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Critical Care

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Safety Data Favor Diuretic Strategy Triggered by Cardiac Monitoring Alerts in HF

Effectiveness of this personalized approach now under investigation

Oct 11, 2024
A photo of an implantable loop recorder in the palm of a man's hand.
Elamipretide for Barth Syndrome Survives FDA Advisory Vote

Panelists acknowledge difficulty generating stronger data in ultra-rare disease

Oct 11, 2024
FDA ADCOMM elamipretide hydrochloride injection over a computer rendering of mitochondria.
FDA Reviewers Cast Doubt on Drug Candidate for Barth Syndrome

Agency appears unswayed by mitochondria-targeting drug for rare cardioskeletal disease

Oct 09, 2024
FDA ADCOMM elamipretide hydrochloride injection over a computer rendering of mitochondria.
Metabolic Accelerator Shows Promise for Weight Loss Side of Obesity-HFpEF Equation

Benefit in symptoms, functional outcomes remains to be seen for HU6

Oct 02, 2024
HFSA over a computer rendering of the human heart.
Mavacamten Shows Promise in Heart Failure With Normal to Supranormal EF

Cardiac myosin inhibitor linked to improvements in biomarkers in small study

Sep 30, 2024
HFSA over a computer rendering of the human heart.
Does Finerenone's Efficacy Diminish if Initiated Late in Heart Failure?

Benefit of the nonsteroidal MRA otherwise consistent across FINEARTS-HF

Sep 29, 2024
HFSA over a computer rendering of the human heart.
Are Regulators the Root of the Problem of Serious Device Recalls?

Study lays out common gaps in evidence both before and after approval

Sep 16, 2024
A photo of Boston Scientific’s Vici venous stents.
Oral Anticoagulation and TAVR Together: A Recipe for Trouble

Continued OAC failed to meet noninferiority in POPular PAUSE TAVI

Sep 03, 2024
ESC over a photo of ExCeL London conference and exhibition center.
Another Trial Sides With MitraClip for Functional Mitral Regurgitation

RESHAPE-HF2 has provocative implications for a wider pool of TEER candidates

Aug 31, 2024
ESC over a photo of ExCeL London conference and exhibition center.
TriClip's 'Soft' Benefits Affirmed in Severe Tricuspid Regurgitation

Randomized trial "highly encouraging" for making patients feel and function better

Aug 31, 2024
ESC over a photo of ExCeL London conference and exhibition center.
Pause or Keep RAS Inhibitors Before Surgery? Take Your Pick.

Either choice is "acceptable" based on randomized study

Aug 31, 2024
ESC over a photo of ExCeL London conference and exhibition center.
Bleeding Better Controlled When Protamine Is Part of TAVR Wrap-Up Routine

ACE-PROTAVI trial tested upfront vs selective use of heparin reversal agent

Aug 14, 2024
A photo of an artificial aortic valve in the fingers of a blue rubber gloved hand.
This U.S. President Was Dying, but His Doctors Zipped Their Lips

Eight decades after FDR's decline and death, do White House physicians owe truth to the public?

Jul 16, 2024
 A photo of the White House.
Diuretics for Ambulatory HF Patients With Volume Overload: Winners & Losers

Three regimens compared head-to-head among abundant choices

Jul 10, 2024
A close up photo of a senior woman’s hand with an intravenous line attached.
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