Meeting Coverage
GuCS
Genitourinary Cancers Symposium
Latest GuCS Meeting Coverage
More fatigue, depression, worse reaction time with enzalutamide as compared with abiraterone
Pembrolizumab leads to improved OS; single-agent nivolumab fails to impact DFS
Multiparametric Stockholm3 avoided far more unnecessary biopsies without sacrificing sensitivity
Benefit more than double with the immune checkpoint inhibitor compared with observation
Combination improved PFS versus more hormonal therapy, but control arm questioned
In small first-line trial, PFS more than doubled with combination
OS, PFS, cancer-specific survival all improved, with no increase in toxicity
Updated trial data show nivolumab/cabozantinib doublet "is getting better with age"
KEYNOTE-057 trial results suggest DFS benefit for patient population with unmet need
But add-on abiraterone and apalutamide may offer some benefits in those with higher PSA
Final PROpel analysis also shows trend toward overall survival improvement with PARP inhibitor
Combination achieved a 37% reduction in risk of progression, death versus ARPI alone
Benefit in selected patients seen over physician's choice of docetaxel or second-generation ARPI
Atezolizumab did show some activity, with a 30% overall response rate
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ASH: Hematology: American Society of Hematology
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ASTRO: American Society for Radiation Oncology
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