Asymmetric disease may occur in one-third of patients with thyroid eye disease, with muscle volume expansion possibly contributing to the asymmetry. A standardized definition of asymmetry using more objective parameters is needed to facilitate comparisons among studies.
Investigators retrospectively reviewed medical records of patients with thyroid eye disease to determine the most useful biomarker for extraocular muscle enlargement.
A South Korean study followed patients with thyroid cancer to assess for risk of Graves’ orbitopathy, finding an association with radioactive iodine treatment.
According to a study from Mayo Clinic, pregnancy-associated plasma protein A has a role in the pathogenesis of thyroid eye disease and may be a more selective target for novel therapies modulating insulin-like growth factor activity, the main driver of TED.